Oxygen free radicals and retinopathy of prematurity.
نویسندگان
چکیده
منابع مشابه
Hypoxia-Induced Oxidative Stress in Ischemic Retinopathy
Oxidative stress plays a crucial role in the pathogenesis of retinal ischemia/hypoxia, a complication of ocular diseases such as diabetic retinopathy (DR) and retinopathy of prematurity (ROP). Oxidative stress refers to the imbalance between the production of reactive oxygen species (ROS) and the ability to scavenge these ROS by endogenous antioxidative systems. Free radicals and ROS are implic...
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Oxidative stress contributes to the severity of several newborn conditions to the extent that Saugstad coined the phrase "oxygen radical diseases of neonatology." In order to counteract free radicals damage many strategies to augment antioxidant status in ill-term and preterm infants have been proposed and several medications have been experimented with mixed results. Several studies have teste...
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Background & Aims: Retinopathy OF prematurity (ROP) is a developmental disorder of retinal vessels in premature neonates. In recent years, because of advances in the care of neonates hospitalized in equipped Intensive care units, retinopathy of prematurity has become a major cause of blindness in those who are survived. This study assessed the incidence and severity of retinopathy and related r...
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Retinopathy of prematurity (ROP) appears to be a multifactorial disease, the prevention of which is probably impossible even with the most accurate methods of blood-gas monitoring and oxygen restrictions. The oxidative processes and consequent formation of free radicals are probably influenced by the availability of various antioxidants in the immature retina. Bilirubin, the end product of haem...
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Background: The most common cause of preventable blindness in children is retinopathy of prematurity (ROP). The most important risk factors for this disease are preterm delivery and low birth weight (LBW). This research was performed to evaluate the prevalence ofand risk factors for ROP in preterm neonates. Methods: Our research was a cross-sectional descriptive and retrospective study conduct...
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ورودعنوان ژورنال:
- The British journal of ophthalmology
دوره 80 5 شماره
صفحات -
تاریخ انتشار 1996